Vancouver , BC , Canada Background Activity of Reverse Transcriptases
نویسندگان
چکیده
images were scanned using a Hewlett Packard 6300 dpi resolution scanner. The MeP footprint of androgen receptor cooperatively bound to DNA revealed for the first time guanines that became hypersensitive to DMS methylation (Figure 1). Since DMS normally methylates guanines uniformly, the hypermethylation of guanine indicates local distortion to the DNA. Therefore, MeP is an ideal footprinting method for detecting local distortion to the DNA that result from allosteric interactions between a transcription factor and the DNA. This method greatly improves the utility of methylation protection as a tool for readily examining DNA-protein interactions.
منابع مشابه
The importance of attenuation correction for coincidence positron tomography on hybrid PET/SPECT gamma camera system
Abstract is NOT available
متن کاملAssessing and Improving Performance: A Longitudinal Evaluation of Priority Setting and Resource Allocation in a Canadian Health Region
Background In order to meet the challenges presented by increasing demand and scarcity of resources, healthcare organizations are faced with difficult decisions related to resource allocation. Tools to facilitate evaluation and improvement of these processes could enable greater transparency and more optimal distribution of resources. Methods The Resource Allocation Performance Assessment Too...
متن کاملPositron tomography of breast cancer in a community hospital: A case study of advanced disease using a coincidence gamma camera
Until recently PET scanning has been available only at major universities or teaching hospitals possessing the necessary resources and expertise to operate a research PET facility. Most dedicated PET centers cost several millions of dollars, and include a cyclotron, a radiochemistry laboratory to synthesize PET radiopharmaceuticals, a multicrystal dedicated PET camera, advanced computer f...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره شماره
صفحات -
تاریخ انتشار 2001